长春花碱、利妥昔单抗与高效抗逆转录病毒治疗法：一名患有多中心性Castleman病的HIV阳性患者的治疗
Vinblastine, rituximab and HAART, treatment of an HIV -positive patient with multicentric Castleman's disease.
作者信息
van Aalderen M C, Brinkman K, van den Berk G E L, Terpstra W E
机构信息
Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
出版信息
Neth J Med. 2010 Feb;68(2):87-90.
An HIV-positive man from Somalia presented with severe malaise, weight loss, relapsing fever, lymphadenopathy and splenomegaly. An FDG-PET-scan-guided lymph node biopsy revealed the characteristic histological features of the plasma cell variant of Castleman's disease. A high HHV-8 viral load was detected in the serum (7980 copies/ml). Treatment with HAART, rituximab and vinblastine resulted in a full and rapid recovery and lowered HHV-8 viral load to undetectable levels.
一名来自索马里的艾滋病毒阳性男子出现严重不适、体重减轻、弛张热、淋巴结病和脾肿大。氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）引导下的淋巴结活检显示了卡斯特曼病浆细胞变异型的特征性组织学特征。血清中检测到高人类疱疹病毒8型（HHV-8）病毒载量（7980拷贝/毫升）。接受高效抗逆转录病毒治疗（HAART）、利妥昔单抗和长春碱治疗后，患者完全且迅速康复，HHV-8病毒载量降至检测不到的水平。
Zotero 插件