大鼠前脑和小脑中几种酸性糖苷酶的产后发育比较。

Comparison of postnatal development of several acid glycosidases in the rat forebrain and cerebellum.

作者信息

Lau H C, Horowitz C, Jumawan J, Koldovsky O

出版信息

Biol Neonate. 1977;32(1-2):97-107. doi: 10.1159/000241001.

PMID:20169

Abstract

Changes of activity of several glycosidases (beta-galactosidase, beta-glucuronidase, N-acetyl-beta-D-glucosaminidase, alpha-D-mannosidase and alpha-L-fucosidase) were compared in the forebrain and cerebellum during postnatal development of the rat. Detailed analysis of the data showed similarities, but also substantial differences in their development in both organs. This is interpreted as an indication of the presence of common regulatory mechanisms, as well as of other factors which differently influence development of the glycosidases studied in both CNS parts.

摘要

在大鼠出生后的发育过程中，比较了前脑和小脑中几种糖苷酶（β-半乳糖苷酶、β-葡萄糖醛酸酶、N-乙酰-β-D-氨基葡萄糖苷酶、α-D-甘露糖苷酶和α-L-岩藻糖苷酶）活性的变化。对数据的详细分析表明，两者在发育过程中存在相似性，但也有显著差异。这被解释为存在共同调节机制以及其他因素的迹象，这些因素对中枢神经系统两个部位所研究的糖苷酶的发育产生不同影响。