Kurt Rengin Aslihan, Gündüz Kaan
Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.
Clin Ophthalmol. 2010 Feb 2;4:59-65. doi: 10.2147/opth.s8660.
To evaluate the results and complications of exoresection via a partial lamellar sclerouvectomy (PLSU) procedure for uveal tumors performed by a novice surgeon without help from an experienced surgeon.
Medical records of 22 patients who underwent exoresection for uveal tumors between February 1999 and January 2009 were evaluated retrospectively. Exoresection was considered for tumors with their epicenter in the iris or in the ciliary body.
Twenty-two patients with a mean age of 45.9 years (range: 19-72 years) were included in this study. The histopathologic diagnosis was uveal malignant melanoma in 16 patients, iridociliary nevus in 2 patients, iris nevus in 2 patients, and iridociliary melanocytoma in 2 patients. Postoperative complications included cataract in 11 patients (50%), scleral thinning in 4 patients (18%), vitreous hemorrhage in 2 patients (9%), hyphema in 2 patients (9%), secondary glaucoma in 2 patients (9%), iridodialysis in 1 patient (4.5%), bullous keratopathy in 1 patient (4.5%), and posterior synechiae in 1 patient (4.5%). At a mean follow-up of 40.1 months (range: 1-98 months), there were no recurrences or metastatic events.
Exoresection seems to be an effective treatment option in selected cases of iridociliary and ciliary body tumors. Novice surgeons with limited training in PLSU should not discourage themselves from doing this type of surgery. Several postoperative complications inevitably occur and require frequent patient monitoring.
评估在无经验丰富的外科医生协助下,新手外科医生通过部分板层巩膜葡萄膜切除术(PLSU)对葡萄膜肿瘤进行外切除术的结果及并发症。
回顾性评估1999年2月至2009年1月间22例行葡萄膜肿瘤外切除术患者的病历。对于以虹膜或睫状体为中心的肿瘤考虑行外切除术。
本研究纳入22例患者,平均年龄45.9岁(范围:19 - 72岁)。组织病理学诊断为葡萄膜恶性黑色素瘤16例,虹膜睫状体痣2例,虹膜痣2例,虹膜睫状体黑色素细胞瘤2例。术后并发症包括白内障11例(50%),巩膜变薄4例(18%),玻璃体出血2例(9%),前房积血2例(9%),继发性青光眼2例(9%),虹膜根部离断1例(4.5%),大泡性角膜病变1例(4.5%),以及虹膜后粘连1例(4.5%)。平均随访40.1个月(范围:1 - 98个月),无复发或转移事件。
外切除术似乎是虹膜睫状体和睫状体肿瘤某些特定病例的有效治疗选择。在PLSU方面训练有限的新手外科医生不应因这类手术而气馁。术后不可避免会出现一些并发症,需要对患者进行频繁监测。