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简化急性生理学评分(SAPS 3)在巴西医院的适用性。

Applicability of the simplified acute physiology score (SAPS 3) in Brazilian hospitals.

作者信息

Silva Junior João Manoel, Malbouisson Luiz M Sá, Nuevo Hector L, Barbosa Luiz Gustavo T, Marubayashi Lauro Yoiti, Teixeira Isabel Cristina, Nassar Junior Antonio Paulo, Carmona Maria Jose Carvalho, Silva Israel Ferreira da, Auler Júnior José Otávio Costa, Rezende Ederlon

机构信息

Serviço de Anestesiologia do Hospital do Servidor Público Estadual Francisco Morato de Oliveira (HSPE), São Paulo, SP.

出版信息

Rev Bras Anestesiol. 2010 Jan-Feb;60(1):20-31.

Abstract

BACKGROUND AND OBJECTIVES

The SAPS 3 (Simplified Acute Physiology Score 3) prognostic system is composed of 20 parameters, represented by an acute physiology score and assessment of the previous status, aimed at establishing a predictive mortality index for patients admitted to intensive care units (ICU). The objective of this study was to validate this system and determine its discriminatory power in surgical patients in Brazil.

METHODS

This is a prospective study undertaken in two surgical ICUs of two different hospitals over a one-year period; patients younger than 16 years, who stay at the ICU for less than 24 hours, readmitted to the unit, and those admitted for dialysis were excluded from the study. The predictive ability of the SAPS 3 index to differentiate survivors and non-survivors was determined by the ROC curve and calibration by the Hosmer-Lemeshow goodness-of-fit test.

RESULTS

One thousand three-hundred and ten patients were included in the study. Gastrointestinal surgeries predominated (34.9%). Eighteen was the lower SAPS 3 index and the highest was 154, with a mean of 48.5 +/- 18.1. The predicted and real hospital mortality was 10.3% and 10.8%, respectively; the standardized mortality ratio (SMR) was 1.04 (95%CI = 1.03-1.07). Calibration by the Hosmer and Lemeshow method showed X(2) = 10.47 p = 0.234. The SAPS 3 score that better discriminated survivors and non-survivors was 57, with sensitivity of 75.8% and specificity 86%. Among the patients with SAPS 3 index higher than 57, 73.5% did not survive versus 26.5% who survived (OR= 1.32, 95%CI 1.23-1.42, p < 0.0001).

CONCLUSIONS

The SAPS 3 system is valid for the Brazilian population of surgical patients, being a useful indicator of critical patients and to determine greater care in this group.

摘要

背景与目的

SAPS 3(简化急性生理学评分3)预后系统由20个参数组成,以急性生理学评分和既往状况评估为代表,旨在为入住重症监护病房(ICU)的患者建立一个预测死亡率指数。本研究的目的是验证该系统并确定其在巴西外科患者中的鉴别能力。

方法

这是一项在两家不同医院的两个外科ICU进行的为期一年的前瞻性研究;年龄小于16岁、在ICU停留时间少于24小时、再次入住该科室以及因透析入院的患者被排除在研究之外。通过ROC曲线确定SAPS 3指数区分存活者和非存活者的预测能力,并通过Hosmer-Lemeshow拟合优度检验进行校准。

结果

1310例患者纳入研究。胃肠道手术占主导(34.9%)。SAPS 3指数最低为18,最高为154,平均为48.5±18.1。预测的和实际的医院死亡率分别为10.3%和10.8%;标准化死亡率(SMR)为1.04(95%CI = 1.03 - 1.07)。采用Hosmer和Lemeshow方法校准显示X(2)=10.47,p = 0.234。能更好区分存活者和非存活者的SAPS 3评分为5生率为26.5%(OR = 1.32,95%CI 1.23 - 1.42,p < 0.0001)。

结论

SAPS 3系统对巴西外科患者群体有效,是危重症患者的有用指标,可用于确定该群体中更优质的护理。 7,敏感性为75.8%,特异性为86%。在SAPS 3指数高于57的患者中,73.5%未存活,而存活

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