Division of Environmental and Water Resources Engineering, School of Civil and Environmental Engineering, Nanyang Technological University, Singapore, Singapore.
Appl Microbiol Biotechnol. 2010 Apr;86(3):825-37. doi: 10.1007/s00253-010-2463-0. Epub 2010 Feb 19.
Microbial attachment to a solid surface is a universal phenomenon occurring in both natural and engineering systems and is responsible for various types of biofouling. Membrane systems have been widely applied in drinking water production, wastewater reuse, and seawater desalination. However, membrane biofouling is the bottleneck that limits the development of membrane systems. In this review, some biological control strategies of microbial attachment which would have great potential in alleviating membrane biofouling are discussed, including inhibition of quorum sensing system, nitric oxide-induced biofilm dispersal, enzymatic disruption of extracellular polysaccharides, proteins, and DNA, inhibition of microbial attachment by energy uncoupling, use of cell wall hydrolases, and disruption of biofilm by bacteriophage. It appears that biological control of microbial attachment would be a novel and promising alternative for mitigating membrane biofouling and would be a new research niche that deserves further study.
微生物附着在固体表面是一种普遍存在于自然和工程系统中的现象，它导致了各种类型的生物污垢。膜系统已广泛应用于饮用水生产、废水再利用和海水淡化。然而，膜生物污垢是限制膜系统发展的瓶颈。在这篇综述中，讨论了一些具有缓解膜生物污垢潜力的微生物附着的生物控制策略，包括群体感应系统的抑制、一氧化氮诱导生物膜分散、胞外多糖、蛋白质和 DNA 的酶促破坏、能量解偶联抑制微生物附着、使用细胞壁水解酶以及噬菌体破坏生物膜。生物控制微生物附着似乎是一种缓解膜生物污垢的新颖而有前途的替代方法，将成为一个值得进一步研究的新研究领域。
