Gerber K, Rees P
J S Afr Vet Assoc. 2009 Sep;80(3):199-203. doi: 10.4102/jsava.v80i3.202.
An 8-month-old crossbred Labrador retriever was presented with a history and clinical signs suggestive of lower urinary tract obstruction. Laboratory results revealed azotaemia and hyperphosphataemia. Ultrasonographic evaluation of the urinary tract showed a mass at the bladder trigone, hydronephrosis, hyrodureter, and suspected metastases to lymph nodes and the liver. Pulmonary metastasis was identified on thoracic radiographs. A post mortem confirmed metastases to the liver, lungs and regional lymph nodes, as well as to the mesenteric lymph nodes, mediastinum, heart, subcutaneous tissue and several muscle groups. A histopathological diagnosis of metastatic botryoid rhabdomyosarcoma (sarcoma botryoides) was made. A review of the literature shows that, although the bladder trigone is a well documented location for this tumour, this case was unique with its widespread metastases to previously undocumented organs. The incidence, embryology, ultrasonographic appearance and treatment of this tumour are discussed.
一只8个月大的杂交拉布拉多寻回犬因有下尿路梗阻的病史和临床症状前来就诊。实验室检查结果显示有氮血症和高磷血症。对尿路进行超声检查发现膀胱三角区有一个肿块、肾积水、输尿管积水，并怀疑有淋巴结和肝脏转移。胸部X光片显示有肺转移。尸检证实有肝、肺、区域淋巴结转移，以及肠系膜淋巴结、纵隔、心脏、皮下组织和几个肌肉群转移。组织病理学诊断为转移性葡萄状横纹肌肉瘤（葡萄状肉瘤）。文献回顾显示，虽然膀胱三角区是该肿瘤一个有充分记录的发病部位，但该病例的独特之处在于其广泛转移到了以前未记录的器官。本文讨论了该肿瘤的发病率、胚胎学、超声表现及治疗方法。
