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[艾司洛尔用于甲状腺危象患者关节镜下滑膜切除术的麻醉管理]

[Anesthetic management using esmolol for arthroscopic synovectomy in a patient with thyroid storm].

作者信息

Torigoe Kei, Suzuki Hiroto, Nakajima Waka, Takahashi Minori, Aoyagi Mitsuo

机构信息

Anesthesia and Analgesia Service, Chiba Aoba Municipal Hospital, Chiba 260-0852.

出版信息

Masui. 2010 Feb;59(2):257-9.

Abstract

We report a case of a 47-year-old woman with past medical history of Graves disease who presented with thyroid storm, a state of physiologic decompensation due to severe thyrotoxicosis, and arthritis purulenta. Antithyroid therapy ameliorated thyrotoxicosis in 4 days, and arthroscopic synovectomy of the right knee was performed. Anesthesia was induced with intravenous propofol. Esmolol, an ultra-short-acting beta blocker listed in national drug tariff of Japan for intraoperative continuous iv infusion in March 2008, was also administered to control heart rate. Then, laryngeal mask airway was inserted and echo-guided femoral nerve block was done with ropivacaine. Anesthesia was maintained with i.v. infusion of propofol and fentanyl. Short episode of supraventricular tachycardia occurred twice, but each tachycardia disappered in about a half minute. The postoperative course was uneventful. Esmolol probably acted to prevent intraoperative tachycardia due to increased beta-adrenergic tone.

摘要

我们报告一例47岁女性,既往有格雷夫斯病病史,此次因甲状腺风暴(一种由于严重甲状腺毒症导致的生理失代偿状态)和脓性关节炎就诊。抗甲状腺治疗在4天内改善了甲状腺毒症,并对右膝进行了关节镜下滑膜切除术。采用静脉注射丙泊酚诱导麻醉。艾司洛尔是一种超短效β受体阻滞剂,于2008年3月被列入日本国家药品价格表,用于术中持续静脉输注以控制心率,也予以使用。然后,插入喉罩气道,并用罗哌卡因进行超声引导下股神经阻滞。通过静脉输注丙泊酚和芬太尼维持麻醉。发生了两次短暂的室上性心动过速,但每次心动过速在约半分钟内消失。术后过程顺利。艾司洛尔可能起到了预防因β肾上腺素能张力增加导致的术中心动过速的作用。

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