Eigenmann P, Chizzolini C
Unité d'allergologie adulte et enfant, Service d'immunologie et allergologie, HUG, 1211 Genève 14.
Rev Med Suisse. 2010 Jan 20;6(232):89-92.
Progresses in allergy in 2009 were particularly noticeable in the field of diagnosis with an increased use of recombinant food allergens; tolerance induction protocols, in particular for egg and milk allergy show promising results for the future; and interesting new possibilities for treatment of mastocytosis with anti-IgE antibodies are reported. Clinical immunology has witnessed advances along two main axes. The first aiming at defining new efficacious therapeutic strategies less toxic compared to those currently in use to control SLE and ANCA-related vasculitis. The second highlights a novel response index appears to be a major advancement toward our understanding of SLE.
2009年过敏领域的进展在诊断方面尤为显著,重组食物过敏原的使用增加;耐受性诱导方案,特别是针对鸡蛋和牛奶过敏的方案显示出未来有希望的结果;并且报告了用抗IgE抗体治疗肥大细胞增多症的有趣新可能性。临床免疫学沿着两个主要方向取得了进展。第一个方向旨在确定比目前用于控制系统性红斑狼疮(SLE)和抗中性粒细胞胞浆抗体(ANCA)相关血管炎的疗法毒性更低的新有效治疗策略。第二个方向突出了一种新的反应指数,这似乎是我们对SLE理解的一个重大进展。