Kothari Shyam S, Sharma Sanjiv, Bhatt Kinjal, Ray Ruma, Bakhshi Sameer, Chowdhury Ujjwal
Department of Cardiology, All-India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
J Med Case Rep. 2010 Feb 22;4:62. doi: 10.1186/1752-1947-4-62.
Recurrent hemorrhagic pericardial effusion in children with no identifiable cause is a rare presentation.
We report the case of a 4-year-old Indian girl who presented with recurrent hemorrhagic pericardial effusion. Diffuse lymphangiomatosis was suspected when associated pulmonary involvement, soft tissue mediastinal mass, and lytic bone lesions were found. Pericardiectomy and lung biopsy confirmed the diagnosis of diffuse lymphangiohemangiomatosis. Partial clinical improvement occurred with thalidomide and low-dose radiotherapy, but our patient died from progressive respiratory failure.
Diffuse lymphangiohemangiomatosis should be considered in the differential diagnosis of hemorrhagic pericardial effusion of unclear cause.
病因不明的儿童复发性出血性心包积液是一种罕见的表现。
我们报告了一名4岁印度女孩的病例，她出现复发性出血性心包积液。当发现伴有肺部受累、纵隔软组织肿块和溶骨性骨病变时，怀疑为弥漫性淋巴管瘤病。心包切除术和肺活检证实了弥漫性淋巴管血管瘤病的诊断。沙利度胺和低剂量放疗使病情部分临床改善，但我们的患者死于进行性呼吸衰竭。
在病因不明的出血性心包积液的鉴别诊断中应考虑弥漫性淋巴管血管瘤病。
