Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC 27514, USA.
Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S10-9. doi: 10.1016/j.ijrobp.2009.07.1754.
The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review summarizes the currently available three-dimensional dose/volume/outcome data to update and refine the normal tissue dose/volume tolerance guidelines provided by the classic Emami et al. paper published in 1991. A "clinician's view" on using the QUANTEC information in a responsible manner is presented along with a description of the most commonly used normal tissue complication probability (NTCP) models. A summary of organ-specific dose/volume/outcome data, based on the QUANTEC reviews, is included.
《临床正常组织效应的定量分析》(QUANTEC)综述总结了目前可用的三维剂量/体积/结果数据,以更新和完善经典的 Emami 等人 1991 年发表的论文中提供的正常组织剂量/体积耐受指南。本文还介绍了一种“临床医生视角”,用于负责任地使用 QUANTEC 信息,并描述了最常用的正常组织并发症概率(NTCP)模型。根据 QUANTEC 综述,还包括了基于器官特异性剂量/体积/结果数据的总结。