共济失调毛细血管扩张症患者血清 IL-8 水平升高。
Elevated serum IL-8 levels in ataxia telangiectasia.
机构信息
Division of Pediatric Pulmonology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
出版信息
J Pediatr. 2010 Apr;156(4):682-4.e1. doi: 10.1016/j.jpeds.2009.12.007. Epub 2010 Feb 20.
PMID:20171651
Abstract
Serum interleukin (IL)-8 levels were measured in 50 patients with ataxia telangiectasia (A-T) and 22 without A-T. In a cross-sectional study, the geometric mean of IL-8 level was significantly higher in the patients with A-T (P <.0001). Elevated serum IL-8 levels in patients with A-T suggest that systemic inflammation may contribute to the disease phenotype.
摘要
检测了 50 名共济失调毛细血管扩张症（A-T）患者和 22 名非 A-T 患者的血清白细胞介素（IL）-8 水平。在一项横断面研究中，A-T 患者的 IL-8 水平几何均数显著更高（P<.0001）。A-T 患者血清 IL-8 水平升高提示全身性炎症可能导致疾病表型。
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