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钆增强磁共振尿路造影在上尿路恶性肿瘤中的应用。

Gadolinium enhanced magnetic resonance urography for upper urinary tract malignancy.

机构信息

Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA.

出版信息

J Urol. 2010 Apr;183(4):1330-65. doi: 10.1016/j.juro.2009.12.031. Epub 2010 Feb 19.

DOI:10.1016/j.juro.2009.12.031
PMID:20171676
Abstract

PURPOSE

We retrospectively evaluated the accuracy of gadolinium enhanced magnetic resonance urography to detect upper urinary tract tumors.

MATERIALS AND METHODS

A total of 91 magnetic resonance urography studies for suspected upper tract malignancy were done in 70 males and 18 females with a mean age of 71.7 years. Breath hold coronal T2-weighted single shot fast spin-echo and breath-hold coronal 3-dimensional T1-weighted spoiled gradient-recalled echo images with fat suppression were obtained during the nephrographic and excretory phases after intravenous injection of gadolinium based contrast material. Two radiologists independently reviewed magnetic resonance images for a tumor by 4 regions (right/left and renal collecting system/ureter). Sensitivity, specificity and accuracy were calculated.

RESULTS

A total of 35 urinary tract regions in 18 males and 7 females with a mean age of 70.4 years were confirmed to have an upper tract malignant tumor and 219 urinary tract regions were confirmed to be tumor-free. Sensitivity, specificity and accuracy to detect upper urinary tract malignancy were 74.3%, 96.8% and 93.7% for reviewer 1, and 62.9%, 96.3% and 91.7% for reviewer 2, respectively. When patients with a ureteral stent or nephrostomy tube were excluded from analysis, sensitivity, specificity and accuracy were 86.2%, 99.5% and 97.7% for reviewer 1, and 72.4%, 97.9% and 94.6% for reviewer 2, respectively.

CONCLUSIONS

Gadolinium enhanced magnetic resonance urography is accurate to detect upper urinary tract malignant tumors.

摘要

目的

我们回顾性评估钆增强磁共振尿路成像检测上尿路肿瘤的准确性。

材料与方法

对 70 名男性和 18 名女性共 91 例行磁共振尿路成像检查,以怀疑上尿路恶性肿瘤,平均年龄 71.7 岁。静脉注射钆对比剂后,行屏气冠状 T2 加权单次激发快速自旋回波和屏气冠状 3 维 T1 加权扰相梯度回波脂肪抑制图像,用于肾实质期和排泄期。两位放射科医生分别通过 4 个区域(右/左和肾盂/输尿管)对磁共振图像进行肿瘤评估。计算敏感性、特异性和准确性。

结果

18 名男性和 7 名女性共 35 个尿路区域,平均年龄 70.4 岁,经证实患有上尿路恶性肿瘤,219 个尿路区域无肿瘤。第 1 位观察者检测上尿路恶性肿瘤的敏感性、特异性和准确性分别为 74.3%、96.8%和 93.7%,第 2 位观察者分别为 62.9%、96.3%和 91.7%。当排除有输尿管支架或肾造瘘管的患者进行分析时,第 1 位观察者的敏感性、特异性和准确性分别为 86.2%、99.5%和 97.7%,第 2 位观察者分别为 72.4%、97.9%和 94.6%。

结论

钆增强磁共振尿路成像术准确检测上尿路恶性肿瘤。

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