Radiation Oncology Department, University of Pittsburgh Cancer Institute, UPMC Shadyside Hospital, Pittsburgh, PA, USA.
Int J Radiat Oncol Biol Phys. 2010 Nov 1;78(3):855-9. doi: 10.1016/j.ijrobp.2009.09.002. Epub 2010 Feb 19.
The incidence of painful bone metastases increases with longer survival times. Although external beam radiation therapy (EBRT) is an effective palliative treatment, it often requires several days from the start of treatment to produce a measurable reduction in pain scores and a qualitative amelioration of patient pain levels. Meanwhile, the use of analgesics remains the best approach early on in the treatment course. We investigated the role of radiation therapists as key personnel for collecting daily pain scores to supplement assessments by physician and oncology nursing staff and manage pain more effectively during radiation treatment.
Daily pain scores were obtained by the radiation therapists for 89 patients undertaking a total of 124 courses of EBRT for bone metastases and compared with pretreatment pain scores. The majority of patients (71%) were treated to 30 Gy (range, 20-37.5) in 10 fractions (range, 8-15 fractions).
One hundred nineteen treatment courses (96%) were completed. Pain scores declined rapidly to 37.5%, 50%, and 75% of the pretreatment levels by Days 2, 4, and 10, respectively. Pain was improved in 91% of patients with only 4% of worse pain at the end of treatment. Improved pain scores were maintained in 83% of patients at 1-month follow-up, but in 35% of them, the pain was worse than at the end of treatment.
Collection of daily pain scores by radiation therapists was associated with an effective reduction in pain scores early on during EBRT of painful osseous metastases.
随着生存时间的延长,疼痛性骨转移的发生率增加。虽然外束放射治疗(EBRT)是一种有效的姑息治疗方法,但从开始治疗到疼痛评分明显下降和患者疼痛水平的定性改善,通常需要数天时间。同时,在治疗过程的早期,使用镇痛药仍然是最佳方法。我们研究了放射治疗师作为关键人员收集每日疼痛评分的作用,以补充医生和肿瘤护理人员的评估,并在放射治疗期间更有效地管理疼痛。
放射治疗师为 89 名接受总共 124 次 EBRT 治疗骨转移的患者收集每日疼痛评分,并与治疗前的疼痛评分进行比较。大多数患者(71%)接受 30Gy(范围 20-37.5)治疗,共 10 个分次(范围 8-15 个分次)。
119 个治疗疗程(96%)完成。疼痛评分分别在第 2、4 和 10 天迅速下降至治疗前水平的 37.5%、50%和 75%。91%的患者疼痛得到改善,只有 4%的患者在治疗结束时疼痛更严重。83%的患者在 1 个月随访时疼痛评分得到改善,但其中 35%的患者疼痛比治疗结束时更严重。
放射治疗师收集每日疼痛评分与 EBRT 治疗疼痛性骨转移早期疼痛评分的有效降低有关。