Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital Halle Saale, Halle, Saale, Germany.
J Neurosci Methods. 2010 May 15;188(2):302-4. doi: 10.1016/j.jneumeth.2010.02.014. Epub 2010 Feb 19.
Low-frequency masking is a psychoacoustical phenomenon, describing the modulation of a high-frequency probe tone burst by a low-frequency masker tone. The probe tone threshold is increased, if the probe tone is presented at a low-frequency phases around 90 degrees and 270 degrees . At these phases, the low-frequency masker tone induces a displacement of the basilar membrane of the inner ear which modulates the sensitivity of the inner hair cells. Measuring the modulation depth is partially applied in clinical routine to diagnose the endolymphatic hydrops. Although the modulation depth differs between normal ears and those which reveal an endolymphatic hydrops, the significance of these tests seems debatable. Here, we describe a new experimental setup, completely consisting of commercially available devices. Further, a user interface was developed to enable the application in the clinical routine. The experimental setup was approved with ten normal hearing listeners. All reveal a modulation of the probe stimulus threshold by different phases of the low-frequency masker stimulus. With this experimental setup, custom-made modifications of the essential parameters are feasible. This would be a contribution to solve open questions on the clinical relevance of the low-frequency masking phenomenon.
低频掩蔽是一种心理声学现象,描述了高频探测音被低频掩蔽音调制的情况。如果探测音在低频相位为 90 度和 270 度左右时出现,那么探测音的阈值会增加。在这些相位,低频掩蔽音会引起内耳基底膜的位移,从而调节内毛细胞的敏感性。测量调制深度部分应用于临床常规,以诊断内淋巴积水。虽然正常耳和内淋巴积水耳之间的调制深度不同,但这些测试的意义似乎存在争议。在这里,我们描述了一种新的实验设置,它完全由市售设备组成。此外,还开发了一个用户界面,以使其能够在临床常规中应用。该实验设置已得到十名正常听力听众的认可。所有人都发现低频掩蔽刺激的不同相位对探测刺激阈值产生了调制。有了这个实验设置,对基本参数的定制修改是可行的。这将有助于解决低频掩蔽现象在临床相关性方面的一些悬而未决的问题。