Livestock Improvement Corp., Hamilton, New Zealand.
J Dairy Sci. 2010 Mar;93(3):1243-52. doi: 10.3168/jds.2009-2619.
A method is described for the prediction of breeding values incorporating genomic information. The first stage involves the prediction of genomic breeding values for genotyped individuals. A novel component of this is the estimation of the genomic relationship matrix in the context of a multi-breed population. Because not all ancestors of genotyped animals are genotyped, a selection index procedure is used to blend genomic predictions with traditional ancestral information that is lost between the process of deregression of the national breeding values and subsequent re-estimation using the genomic relationship matrix. Finally, the genomically enhanced predictions are filtered through to nongenotyped descendants using a regression procedure.
描述了一种结合基因组信息预测育种值的方法。第一阶段涉及对已基因型个体的基因组育种值进行预测。这一阶段的一个新组件是在多品种群体的背景下估计基因组关系矩阵。由于并非所有基因型动物的祖先都是基因型的,因此使用选择指数程序将基因组预测与传统的祖先信息混合,这些信息在国家育种值去回归和随后使用基因组关系矩阵重新估计之间丢失。最后,使用回归程序通过回归程序将基因组增强的预测过滤到非基因型后代。