治疗咳嗽的未来方向。

Future directions in treating cough.

作者信息

McGarvey Lorcan P A, Elder Jennifer

机构信息

Centre for Infection and Immunity, The Queen's University of Belfast, Belfast, Northern Ireland, UK.

出版信息

Otolaryngol Clin North Am. 2010 Feb;43(1):199-211, xii. doi: 10.1016/j.otc.2009.11.011.

DOI:10.1016/j.otc.2009.11.011

PMID:20172268

Abstract

Cough is a common and troublesome symptom that can be difficult to treat. New therapeutic options that are safe and more effective than those currently available are needed. In this article, the authors offer opinion on future directions in the treatment of cough, with a particular emphasis on the clinical syndrome associated with cough reflex hypersensitivity. In addition, the article provides an overview of some of the diagnostic technologies and promising drug targets likely to emerge from current clinical and scientific endeavor.

摘要

咳嗽是一种常见且令人困扰的症状，可能难以治疗。需要有比现有治疗方法更安全、更有效的新治疗选择。在本文中，作者就咳嗽治疗的未来方向发表了看法，特别强调了与咳嗽反射超敏相关的临床综合征。此外，本文还概述了一些可能从当前临床和科学研究中出现的诊断技术和有前景的药物靶点。