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慢性化脓性中耳炎中砧骨坏死的术前预测因素。

Preoperative predictors of incudal necrosis in chronic suppurative otitis media.

机构信息

Department of ENT, Speech and Hearing, Christian Medical College Hospital, Vellore, India.

出版信息

Otolaryngol Head Neck Surg. 2010 Mar;142(3):415-20. doi: 10.1016/j.otohns.2009.11.026.

DOI:10.1016/j.otohns.2009.11.026
PMID:20172391
Abstract

OBJECTIVE

To determine the predictive value of preoperative clinical, audiological, and radiological factors in diagnosing incudal necrosis in patients with tubotympanic chronic suppurative otitis media (CSOM).

STUDY DESIGN

Case series with planned data collection.

SETTING

Tertiary care referral center.

SUBJECTS AND METHODS

Patients older than five years of age diagnosed with tubotympanic CSOM who underwent tympanomastoid surgery were recruited. Findings on otoscopy, x-ray mastoid, pure-tone audiometry, and intraoperative otomicroscopy were recorded.

RESULTS

Incus necrosis occurred in 24 (16%) of a total of 150 patients. On bivariate analysis, findings of active ear discharge (P = 0.01), anterosuperior location of perforation (P = 0.03), exposure of incudostapedial joint (P = 0.05), edematous middle ear mucous membrane (P = 0.05), middle ear granulations (P = 0.004), foreshortening of the handle of malleus (P = 0.04), moderate to moderately severe hearing loss (41-70 dB HL) (P = 0.000), and air-bone gap > 40 dB (P = 0.001) were found to be associated with incus necrosis. Intraoperative findings of aditus block (P = 0.001) and mastoid granulations (P = 0.005) were also found to be significantly associated with incus necrosis. Mastoid pneumatization and perforation size and site were not associated with incus necrosis. On multivariate analysis, only middle ear granulations (P = 0.04; odds ratio [OR] 3.161; 95% confidence interval [95% CI] 1.087-9.196) and a moderate to moderately severe hearing loss (41-70 dB HL) (P = 0.03; OR 1.720; CI 1.064-2.782) were found to be significant risk factors.

CONCLUSION

Incus necrosis is best predicted by the presence of middle ear granulations and moderate to moderately severe hearing loss (41-70 dB HL). Knowledge of this information preoperatively can influence surgical decision making and preparedness regarding ossiculoplasty and patient consent.

摘要

目的

确定术前临床、听力学和影像学因素对诊断慢性化脓性中耳炎(CSOM)患者砧骨坏死的预测价值。

研究设计

病例系列,计划数据收集。

设置

三级转诊中心。

受试者和方法

招募年龄大于 5 岁、诊断为慢性化脓性中耳炎伴鼓窦乳突的患者。记录耳镜检查、乳突 X 线、纯音测听和术中耳镜检查的结果。

结果

150 例患者中共有 24 例(16%)发生砧骨坏死。在单变量分析中,有活动性耳溢(P=0.01)、前上穿孔位置(P=0.03)、砧镫关节暴露(P=0.05)、中耳黏膜水肿(P=0.05)、中耳肉芽(P=0.004)、锤骨柄缩短(P=0.04)、中度至中度严重听力损失(41-70 dB HL)(P=0.000)和骨气导差>40 dB(P=0.001)的发现与砧骨坏死有关。术中发现鼓窦入口阻塞(P=0.001)和乳突肉芽(P=0.005)也与砧骨坏死显著相关。乳突气化和穿孔大小及位置与砧骨坏死无关。多变量分析显示,只有中耳肉芽(P=0.04;优势比[OR]3.161;95%置信区间[95%CI]1.087-9.196)和中度至中度严重听力损失(41-70 dB HL)(P=0.03;OR 1.720;CI 1.064-2.782)是显著的危险因素。

结论

中耳肉芽和中度至中度严重听力损失(41-70 dB HL)最能预测砧骨坏死。术前了解这些信息可以影响手术决策,并为镫骨成形术和患者知情同意做好准备。

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