Suppr超能文献

鼓室-乳突炎、胆脂瘤和鼓膜内陷患者的感音神经性听力损失的预测因素。

Predictors for sensorineural hearing loss in patients with tubotympanic otitis, cholesteatoma, and tympanic membrane retractions.

机构信息

School of Medicine University of Belgrade, Serbia.

出版信息

Otol Neurotol. 2012 Aug;33(6):934-40. doi: 10.1097/MAO.0b013e318259b885.

Abstract

OBJECTIVE

To determine predicting value of otitis type, age, gender, ear suppuration, disease duration, mucosal changes, cholesteatoma spreading, labyrinthine fistula, size, localization of tympanic membrane perforation, type and stage of its retraction and ossicular chain disruption with sensorineural hearing loss in patients with tubotympanic otitis, cholesteatoma, and tympanic membrane retractions.

STUDY DESIGN

Retrospective case review study.

SETTING

Tertiary referral center.

PATIENTS

Approximately 264 adult patients with unilateral chronic ear disease, 60 adult patients with tympanic membrane retractions, 78 with cholesteatoma, and 126 with tubotympanic otitis.

INTERVENTIONS

Otomicroscopy, pure tone audiometry, impedancemetry were carried out preoperatively. Wall up, wall down tympanoplasty, or two-stage surgery was applied depending on pathology.

MAIN OUTCOME MEASURE

Bone conduction thresholds for 512 to 4,096 Hz.

RESULTS

Mean values of bone conduction thresholds for frequencies 512 to 4,096 Hz were significantly higher in otitis groups than in healthy ears (p = 0.000), without differences between the groups. Ossicular disruption correlated with sensorineural hearing loss in cholesteatoma and tubotympanic otitis for all frequencies; long incus process destruction in tubotympanic ears showed strong negative correlation with sensorineural hearing loss for 512 to 2,048 Hz (linear regression coefficient, intercept was -2.84, -2.48, and -2.41; p = 0.0024, 0.0207, and 0.0076, respectively). Perforation size correlated with sensorineural hearing loss for 512 to 2,048 Hz in tubotympanic otitis (Log regression p = 0.0008, 0.0252, and 0.0267; odds ratio, 1.13, 1.11, and 1.06). Atelectasis correlated with sensorineural hearing loss for 4,096 Hz (p = 0.022).

CONCLUSION

Predictors for sensorineural hearing loss in chronic otitis are otitis itself, age, ossicular disruption, especially of long incus process, extensive labyrinthine fistula, perforation size, and type of retraction.

摘要

目的

确定中耳炎类型、年龄、性别、耳流脓、病程、黏膜变化、胆脂瘤扩散、迷路瘘管、大小、鼓膜穿孔位置、鼓膜内陷及其回缩和听骨链破坏的类型和阶段与鼓室-乳突炎、胆脂瘤和鼓膜内陷患者的感音神经性听力损失之间的预测价值。

研究设计

回顾性病例研究。

设置

三级转诊中心。

患者

约 264 名单侧慢性耳部疾病的成年患者,60 名鼓膜内陷的成年患者,78 名胆脂瘤患者和 126 名鼓室-乳突炎患者。

干预措施

术前进行耳镜检查、纯音测听和阻抗测量。根据病理情况,应用鼓室成形术、鼓室成形术加乳突切除术或二期手术。

主要观察指标

512 至 4096 Hz 的骨导阈值。

结果

512 至 4096 Hz 频率的骨导阈值平均值在中耳炎组明显高于健康耳(p=0.000),但组间无差异。在胆脂瘤和鼓室-乳突炎中,听骨链破坏与感音神经性听力损失相关;在鼓室-乳突炎中,长砧骨体破坏与 512 至 2048 Hz 的感音神经性听力损失呈强负相关(线性回归系数,截距分别为-2.84、-2.48 和-2.41;p=0.0024、0.0207 和 0.0076)。在鼓室-乳突炎中,穿孔大小与 512 至 2048 Hz 的感音神经性听力损失相关(Log 回归 p=0.0008、0.0252 和 0.0267;比值比,1.13、1.11 和 1.06)。鼓室-乳突炎患者中鼓室萎陷与感音神经性听力损失相关(p=0.022)。

结论

慢性中耳炎患者感音神经性听力损失的预测因素包括中耳炎本身、年龄、听骨链破坏,尤其是砧骨长突破坏、广泛的迷路瘘管、穿孔大小和鼓膜内陷类型。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验