Department of Neurosurgery, Chiba Hokusoh Hospital, Nippon Medical School, 1715 Kamagari, Inba, Chiba 270-1694, Japan.
J Clin Neurosci. 2010 Apr;17(4):450-4. doi: 10.1016/j.jocn.2009.07.118. Epub 2010 Feb 20.
Autologous bone grafts from cervical vertebral bodies (Williams-Isu method) are used for anterior fusion of the cervical spine. When adequate amounts of bone cannot be harvested from the vertebral body, hydroxyapatite (a ceramic) is placed between the bone grafts (the sandwich method). We conducted a radiological study to examine the efficacy of the sandwich method by comparing the alignment of the whole spine and the fused segment between patients who had received a sandwich graft (n=20) and a control group (n=20). Although there was no difference between the two groups with respect to the alignment of the whole spine, the alignment and height of the fused segment was significantly better in the patients in the sandwich graft group. In both groups the position of the anterior edge of the graft and the loss in the angle of the fused segment were significantly correlated (p<0.05). We found that the sandwich method not only reinforced the graft, but also yielded better results with respect to the angle and height of the fused segment.
采用自体颈椎椎体骨（Williams-Isu 法）进行颈椎前路融合。当从椎体获得的骨量不足时，在骨移植物之间放置羟基磷灰石（陶瓷）（夹心方法）。我们通过比较接受夹心移植物（n=20）和对照组（n=20）的患者的整个脊柱和融合节段的对齐情况，进行了一项放射学研究，以检查夹心方法的疗效。尽管两组在整个脊柱的对齐方面没有差异，但夹心移植物组的融合节段的对齐和高度明显更好。在两组中，移植物前缘的位置和融合节段角度的丢失均具有显著相关性（p<0.05）。我们发现夹心法不仅增强了移植物，而且还改善了融合节段的角度和高度。
