Department of Clinical Neurophysiology; Marqués de Valdecilla University Hospital, Santander, Cantabria, Spain.
Epileptic Disord. 2010 Mar;12(1):69-74. doi: 10.1684/epd.2010.0292. Epub 2010 Mar 12.
We describe the case of a 62-year-old man who developed stimulus-induced focal motor seizures after prolonged cardiac arrest. During a video-EEG study, these focal motor seizures progressed into a generalised myoclonic status epilepticus. Both the severely decremented background activity on the EEG, and the absence of median and trigeminal somatosensory evoked potentials were in keeping with a devastating post-hypoxic encephalopathy and the patient died. Our clinical and electrophysiology data suggest that generalised myoclonic status epilepticus may occur in patients in whom the existence of severe cerebral damage prevents a complete development of all phases of classic generalised tonic-clonic seizures.
我们描述了一例 62 岁男性患者,在长时间心脏骤停后出现刺激诱导的局灶性运动性癫痫发作。在视频脑电图研究中,这些局灶性运动性癫痫发作进展为全面性肌阵挛性癫痫持续状态。脑电图上背景活动严重降低,以及正中神经和三叉神经体感诱发电位缺失,与严重缺氧后脑病一致,患者死亡。我们的临床和电生理学数据表明,全面性肌阵挛性癫痫持续状态可能发生在严重脑损伤阻止经典全面性强直-阵挛性发作所有阶段完全发展的患者中。