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[2例中间型β地中海贫血患者的脊髓和马尾神经受压]

[Spinal cord and cauda equina compression in 2 patients with beta-thalassemia intermedia].

作者信息

Coraddu M, Floris F, Meleddu V, Nurchi G C, Cacace E, Contini R, Perpignano G

机构信息

Service de Neurochirurgie, Hôpital G. Brotzu, Cagliari.

出版信息

Neurochirurgie. 1991;37(1):58-60.

PMID:2017295
Abstract

Spinal cord compression as a consequence of mass lesions due to extramedullary hematopoiesis is a well described but rare syndrome occurring in thalassemia and some other hematologic conditions. The authors report two cases of patients with a genetic variant of beta-thalassemia, who suffered from a progressive compression of the spinal cord in one case, of the cauda equina in the other caused by epidural hematopoietic tissue. The first patient recovered after partial surgical removal of this tissue and subsequent radiotherapy. The second one recovered after only radiotherapy.

摘要

髓外造血引起的肿块性病变导致的脊髓压迫是一种在重型地中海贫血和其他一些血液系统疾病中已有充分描述但较为罕见的综合征。作者报告了两例β地中海贫血基因变异患者的病例,其中一例患者脊髓受到渐进性压迫,另一例患者马尾神经受到硬膜外造血组织压迫。第一例患者在部分手术切除该组织并随后进行放射治疗后康复。第二例患者仅通过放射治疗后康复。

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