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[哮喘患者疾病控制情况评估]

[Assessment of disease control in patients with asthma].

作者信息

Pilkauskaite Guoda, Malakauskas Kestutis, Sakalauskas Raimundas

机构信息

Department of Pulmonology and Immunology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania.

出版信息

Medicina (Kaunas). 2009;45(12):943-51.

Abstract

UNLABELLED

International guidelines indicate that the main criterion of asthma management is asthma control level. The aim of this study was to assess asthma control and its relation with age, gender, and lung function.

MATERIAL AND METHODS

A total of 106 family physicians and 13 pulmonologists and allergists took part in this study. Each doctor had selected 10-15 asthma patients and had sent invitations to them by post. On the visit day, the patients themselves filled in the Asthma Control Test. The doctors interviewed the patients and filled in a special questionnaire. Pulmonologists and allergists also assessed lung function by performing spirometry. According to the results of the Asthma Control Test, the disease control level was indicated as "totally controlled" (25 points), "well controlled" (24-20 points), and "uncontrolled" (19 points or less).

RESULTS

A total of 876 asthma patients were examined. Uncontrolled asthma was diagnosed to 56.2% of the patients, 36.5% of patients had well controlled and 7.3% totally controlled asthma. There was no significant difference in asthma control level comparing men and women. A correlation between asthma control level and age was found revealing poorer asthma control in older patients. Ninety-five percent of patients were treated with inhaled steroids; most of them had used inhaled steroids in combination with long-acting beta(2) agonists. It was found that lung function correlated with clinical symptoms of asthma, the demand of short-acting beta(2) agonists, and asthma control level.

CONCLUSION

The study showed that uncontrolled asthma was diagnosed to more than half of the patients, despite most of them used inhaled steroids. Asthma control was worsening with the age of patients with asthma and it correlated with lung function. We suggest that periodical assessment of asthma control should help to optimize asthma management.

摘要

未标注

国际指南指出,哮喘管理的主要标准是哮喘控制水平。本研究的目的是评估哮喘控制情况及其与年龄、性别和肺功能的关系。

材料与方法

共有106名家庭医生以及13名肺科医生和过敏症专科医生参与了本研究。每位医生挑选了10至15名哮喘患者,并通过邮寄方式向他们发出邀请。在就诊当天,患者自行填写哮喘控制测试表。医生对患者进行访谈并填写一份特殊问卷。肺科医生和过敏症专科医生还通过进行肺功能测定来评估肺功能。根据哮喘控制测试结果,疾病控制水平分为“完全控制”(25分)、“良好控制”(24 - 20分)和“未控制”(19分及以下)。

结果

共检查了876名哮喘患者。56.2%的患者被诊断为哮喘未控制,36.5%的患者哮喘得到良好控制,7.3%的患者哮喘完全控制。比较男性和女性,哮喘控制水平无显著差异。发现哮喘控制水平与年龄之间存在相关性,表明老年患者的哮喘控制较差。95%的患者接受吸入性类固醇治疗;其中大多数人将吸入性类固醇与长效β₂激动剂联合使用。发现肺功能与哮喘临床症状、短效β₂激动剂的使用需求以及哮喘控制水平相关。

结论

该研究表明,尽管大多数患者使用了吸入性类固醇,但仍有超过一半的患者被诊断为哮喘未控制。哮喘控制随着哮喘患者年龄的增长而恶化,并且与肺功能相关。我们建议定期评估哮喘控制情况应有助于优化哮喘管理。

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