Nogarède Cécile, Tondeur Marianne, Piepsz Amy
Department of Radioisotopes, CHU St Pierre, Brussels, Belgium.
Nucl Med Commun. 2010 May;31(5):355-8. doi: 10.1097/MNM.0b013e328333151c.
Values for output efficiency (OE) and normalized residual activity (NORA) in paediatric patients have been published previously. However, it is now a usual practice to inject furosemide at the beginning of a renogram acquisition (F0 procedure). The aim was to evaluate OE and NORA obtained on F0 renograms, in normal and abnormal paediatric kidneys.
Three groups of kidneys were selected: group 1, normal kidneys (n=155); group 2, dilated but unobstructed kidneys (n=20); and group 3, hydronephrotic kidneys (n=84). A 20-min Tc-mercaptoacetyltriglycine renogram was obtained under early furosemide injection (F0) and was completed by late postmicturition (PM) images. OE and NORA were calculated at the end of the renogram and on the PM images.
Group 1: NORA and OE calculated at the end of the F0 renogram revealed better drainage than without F0 stimulation. The PM parameters were comparable with those previously obtained after late furosemide injection (F+20). Group 2: the drainage, despite the early injection of furosemide, was often unsatisfactory at the end of the F0 renogram, but improved dramatically upon the PM acquisition. Group 3: almost normal values up to very abnormal ones were observed. In 35% of kidneys, the values of drainage were out of the range of group 2.
Under early furosemide injection, renal drainage in the normal kidneys was better than in basic conditions. In dilated unobstructed kidneys, NORA and OE obtained on late images after micturition were, respectively, below 1.5 and above 80%.
先前已公布小儿患者的输出效率（OE）和标准化残余活性（NORA）值。然而，目前在肾图采集开始时注射呋塞米（F0程序）是一种常见做法。目的是评估在F0肾图上获得的正常和异常小儿肾脏的OE和NORA。
选择三组肾脏：第1组，正常肾脏（n = 155）；第2组，扩张但无梗阻的肾脏（n = 20）；第3组，肾积水肾脏（n = 84）。在早期注射呋塞米（F0）的情况下获得20分钟的锝-巯基乙酰三甘氨酸肾图，并通过排尿后（PM）晚期图像完成。在肾图结束时和PM图像上计算OE和NORA。
第1组：在F0肾图结束时计算的NORA和OE显示出比未进行F0刺激时更好的引流。PM参数与先前在晚期注射呋塞米（F + 20）后获得的参数相当。第2组：尽管早期注射了呋塞米，但在F0肾图结束时引流通常不令人满意，但在PM采集时显著改善。第3组：观察到几乎正常的值到非常异常的值。在35%的肾脏中，引流值超出第2组范围。
在早期注射呋塞米的情况下，正常肾脏的肾引流优于基本情况。在扩张但无梗阻的肾脏中，排尿后晚期图像上获得的NORA和OE分别低于1.5和高于80%。
