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儿童99mTc-MAG3利尿肾图:F0与F+20的比较

99mTc-MAG3 diuretic renography in children: a comparison between F0 and F+20.

作者信息

Donoso G, Kuyvenhoven J D, Ham H, Piepsz A

机构信息

Department of Nuclear Medicine, Centre Hospitalo-Universitaire St Pierre, Brussels, Belgium.

出版信息

Nucl Med Commun. 2003 Nov;24(11):1189-93. doi: 10.1097/00006231-200311000-00010.

DOI:10.1097/00006231-200311000-00010
PMID:14569174
Abstract

The aim of this work was to compare the quality of renal drainage obtained with two well-described procedures of diuretic renography (F+20 and F0 tests). We selected 36 clinically stable children, aged 10 days to 17 years, with unilateral (25) or bilateral (11) hydronephrosis, in whom both F+20 and F0 tests were successively performed. In all cases, a late image (PM) was acquired after micturition and after changing the position of the patient. The following parameters were calculated: the time to the maximum of the basic renogram (Tmax); and the normalized residual activity (NORA) and output efficiency (OE) at the end of the 20 min renogram, at the end of the furosemide test (35 min) and on the PM image. In F+20, the renal drainage was better on the PM image than at the end of the diuretic renogram, whereas, in F0, the renal drainage was better on the PM image than at the end of the 20 min diuretic renogram. When comparing F0 and F+20, both OE and NORA parameters revealed slightly better drainage at the end of the 20 min F0 renogram than at the end of the 35 min F+20 diuretic renogram. The drainage obtained on the late post-voiding image was comparable for both F0 and F+20 tests. In conclusion, the quality of drainage obtained during the F+20 and F0 procedures can easily be compared using both OE and NORA. A very similar quality of drainage was reached for both procedures when considering only the PM image. This PM view remains mandatory irrespective of the timing of the furosemide injection and despite the use of tracers with a high extraction rate.

摘要

这项工作的目的是比较两种已详细描述的利尿肾图检查程序(F + 20和F0试验)所获得的肾引流质量。我们选择了36名临床稳定的儿童,年龄在10天至17岁之间,患有单侧(25例)或双侧(11例)肾积水,对他们依次进行了F + 20和F0试验。在所有病例中,排尿后并改变患者体位后采集延迟图像(PM)。计算了以下参数:肾图曲线达到最大值的时间(Tmax);以及在20分钟肾图检查结束时、速尿试验结束时(35分钟)和PM图像上的标准化残余活性(NORA)和输出效率(OE)。在F + 20试验中,PM图像上的肾引流比利尿肾图检查结束时更好,而在F0试验中,则是PM图像上的肾引流比20分钟利尿肾图检查结束时更好。比较F0和F + 20时,OE和NORA参数均显示,20分钟F0肾图检查结束时的引流略优于35分钟F + 20利尿肾图检查结束时。F0和F + 20试验在排尿后延迟图像上获得 的引流情况相当。总之,使用OE和NORA可以轻松比较F + 20和F0检查过程中获得的引流质量。仅考虑PM图像时,两种检查程序的引流质量非常相似。无论速尿注射时间如何,也不管使用的示踪剂提取率有多高,PM视图都是必不可少的。

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