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游离皮瓣存活,尽管血管蒂早期丢失。

Free flap survival despite early loss of the vascular pedicle.

机构信息

Department of Otolaryngology, Naval Medical Center San Diego, San Diego, CA, USA.

出版信息

Head Neck. 2011 Jul;33(7):1068-71. doi: 10.1002/hed.21354. Epub 2010 Feb 19.

Abstract

BACKGROUND

Early success of microvascular free tissue transfer is dependent upon the patency of the primary vascular pedicle. In time, neovascularization from the recipient bed and surrounding wound margins into the graft may be sufficient to maintain flap viability. The time necessary for successful neovascularization to occur is unclear. Most believe that prior radiation therapy will delay this process.

METHODS

This case report describes a patient, status postchemoradiotherapy, who underwent composite resection with anterolateral thigh free flap reconstruction for a new base of tongue squamous cell carcinoma. On postoperative day 9 the vascular pedicle thrombosed secondary to abscess formation.

RESULTS

Despite early loss of the arterial and venous pedicle, the flap survived completely.

CONCLUSION

After microvascular free tissue transfer, neovascularization sufficient to maintain flap viability independent of the primary vascular pedicle may occur by postoperative day 9. This early revascularization can also occur despite a history of radiotherapy.

摘要

背景

微血管游离组织移植的早期成功取决于主要血管蒂的通畅性。随着时间的推移,来自受区床和周围伤口边缘的新生血管可能足以维持皮瓣的存活。成功发生新生血管化所需的时间尚不清楚。大多数人认为先前的放射治疗会延迟这一过程。

方法

本病例报告描述了一位接受化疗和放疗后的患者,因舌前鳞状细胞癌新基底而行股前外侧游离皮瓣复合切除术。术后第 9 天,血管蒂因脓肿形成而发生血栓。

结果

尽管动脉和静脉蒂早期丧失,但皮瓣完全存活。

结论

微血管游离组织移植后,即使有放疗史,也可能在术后第 9 天发生足以维持皮瓣存活的独立于主要血管蒂的新生血管化。这种早期再血管化也可能发生。

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