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头颈部重建手术中的血管并发症与游离皮瓣挽救:150例再次探查分析

Vascular Complications and Free Flap Salvage in Head and Neck Reconstructive Surgery: Analysis of 150 Cases of Reexploration.

作者信息

Chiu Yen-Hao, Chang Dun-Hao, Perng Cherng-Kang

机构信息

From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital; †School of Medicine, National Yang-Ming University; ‡Division of Plastic and Reconstructive Surgery, Department of Surgery, Far Eastern Memorial Hospital Taiwan, Republic of China.

出版信息

Ann Plast Surg. 2017 Mar;78(3 Suppl 2):S83-S88. doi: 10.1097/SAP.0000000000001011.

Abstract

INTRODUCTION

Despite the excellent reliability of free tissue transfer, flap failure is devastating, and in addition to patient morbidity, it may increase hospital stay and associated costs. Previous studies have evaluated factors related to flap salvage, regarding the operative strategy for flap salvage surgery. The present study aimed to share our experience of reexploration and describe operative standards dealing with vascular thrombosis.

METHODS

We retrospectively reviewed 150 (of 1258) free flaps for head and neck reconstruction that showed signs of vascular compromise at our institution during a 13-year period between 2002 and 2015. Patient demographics, including sex, age, premorbid health status, personal history, indication for reexploration, flap type, and number of recipient vessels, were analyzed. Days between the end of initial surgery and salvage surgery were also recorded. The incidence of postsalvage complications (hematoma formation, wound dehiscence, and infection requiring surgical intervention) and the overall flap survival were recorded.

RESULTS

Of the 150 flaps, 87 flaps had evident arterial or venous thrombosis; 34 of these failed and required a second free flap or pedicle flap reconstruction. The remaining 53 were successfully salvaged. Although vascular thrombosis was found to be a major contributing factor in flap loss, no significant differences in any factor were found between patients with salvageable flaps and those with unsalvageable flaps.

CONCLUSIONS

Vascular thrombosis is a major contributing factor in flap loss. The incidence of venous thrombosis is higher, but arterial thrombosis may be more severe. Improvements in the surgical technique and perioperative management are highly reliable. We believe that strict models of flap monitoring; well-trained, dedicated staff; and immediate reexploration will potentially further improve flap survival and optimize the quality of life.

摘要

引言

尽管游离组织移植具有出色的可靠性,但皮瓣失败的后果是毁灭性的,除了患者的发病率外,还可能增加住院时间和相关费用。先前的研究评估了与皮瓣挽救相关的因素,涉及皮瓣挽救手术的操作策略。本研究旨在分享我们再次手术探查的经验,并描述处理血管血栓形成的手术标准。

方法

我们回顾性分析了2002年至2015年期间在我院进行的1258例用于头颈部重建的游离皮瓣中出现血管受损迹象的150例。分析了患者的人口统计学特征,包括性别、年龄、病前健康状况、个人病史、再次手术探查的指征、皮瓣类型和受区血管数量。还记录了初次手术结束至挽救手术之间的天数。记录了挽救手术后并发症(血肿形成、伤口裂开和需要手术干预的感染)的发生率以及皮瓣的总体存活率。

结果

在这150例皮瓣中,87例出现明显的动脉或静脉血栓形成;其中34例失败,需要进行第二次游离皮瓣或带蒂皮瓣重建。其余53例成功挽救。虽然血管血栓形成被发现是皮瓣丢失的主要因素,但在可挽救皮瓣的患者和不可挽救皮瓣的患者之间,任何因素均未发现显著差异。

结论

血管血栓形成是皮瓣丢失的主要因素。静脉血栓形成的发生率较高,但动脉血栓形成可能更严重。手术技术和围手术期管理的改进具有高度可靠性。我们认为,严格的皮瓣监测模式;训练有素、专注的工作人员;以及立即再次手术探查可能会进一步提高皮瓣存活率并优化生活质量。

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