Department of Chemistry and Biochemistry, Worcester Polytechnic Institute, Worcester, Massachusetts 01609, USA.
Langmuir. 2010 Mar 2;26(5):3731-8. doi: 10.1021/la902966b.
A method for developing complex nanopatterns on surfaces has been developed by combining self-assembly, photolabile protecting groups, and multilayered films. An o-nitrobenzyl protecting group has been incorporated into molecular level films utilizing thiol-gold interactions. When the o-nitrobenzyl group is cleaved by ultraviolet light, a carboxylic acid terminated layer remains on the surface and is available for activation and further functionalization through amide bond formation. Using this method, multilayered films have been constructed and characterized by contact angle goniometry, cyclic voltammetry, grazing incidence infrared spectroscopy, and X-ray photoelectron spectroscopy measurements. Complex surface patterns can be achieved by creating a surface array using a photomask and then further functionalizing the irradiated area through covalent coupling. Fluorophores were attached to the deprotected regions, providing visual evidence of surface patterning using fluorescence microscopy. This approach is universal to bind moieties containing free amine groups at defined regions across a surface, allowing for the development of films with complex chemical and physicochemical properties.
已经开发出一种在表面上形成复杂纳米图案的方法，该方法结合了自组装、光不稳定保护基团和多层膜。利用巯基-金相互作用将邻硝基苄基保护基团纳入分子级薄膜中。当邻硝基苄基基团被紫外光裂解时，羧酸末端层留在表面上，可通过酰胺键形成进行激活和进一步功能化。使用这种方法，通过接触角测量、循环伏安法、掠入射红外光谱和 X 射线光电子能谱测量构建和表征了多层膜。通过使用光掩模创建表面阵列，然后通过共价偶联进一步官能化照射区域，可以实现复杂的表面图案。将荧光团附着到非保护区域，通过荧光显微镜提供表面图案的直观证据。这种方法适用于在表面的指定区域结合含有游离胺基的部分，允许开发具有复杂化学和物理化学性质的薄膜。
