Tatsas Amy D, Keedy Vicki L, Florell Scott R, Simpson Jean F, Coffin Cheryl M, Kelley Mark C, Cates Justin M M
Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
J Cutan Pathol. 2010 Aug;37(8):901-6. doi: 10.1111/j.1600-0560.2010.01512.x. Epub 2010 Feb 8.
Cutaneous angiosarcoma can sometimes mimic other benign and malignant lesions, thereby presenting a difficult differential diagnosis. In the two cases of cutaneous angiosarcoma presented herein, extensive foamy cell alteration of tumor cells resembled a reactive xanthogranulomatous process. Foamy cell angiosarcoma is an unusual and deceptively benign morphologic variant of cutaneous angiosarcoma. Critical features for diagnosis include the presence of a deep, permeative, sometimes 'scaffolding' growth pattern and subtle areas of vascular formation.
皮肤血管肉瘤有时可模仿其他良性和恶性病变，从而造成鉴别诊断困难。在本文报道的两例皮肤血管肉瘤中，肿瘤细胞广泛的泡沫细胞改变类似于反应性黄色肉芽肿性病变。泡沫细胞血管肉瘤是皮肤血管肉瘤一种不常见且看似良性的形态学变异型。诊断的关键特征包括存在深部、浸润性、有时呈“支架样”的生长模式以及微小的血管形成区域。
