CIRAD, UR Animal et Gestion Intégrée des Risques (AGIRs), Montpellier, France.
Epidemiol Infect. 2010 Nov;138(11):1601-9. doi: 10.1017/S095026881000035X. Epub 2010 Feb 23.
In 2005, a serological study was carried out on horses in five ecologically contrasted zones of the Senegal River basin (Senegal) to assess West Nile virus (WNV) transmission and investigate underlying environmental risk factors. In each study zone, horses were randomly selected and blood samples taken. A land-cover map of the five study areas was built using two satellite ETM+ images. Blood samples were screened by ELISA for anti-WNV IgM and IgG and positive samples were confirmed by seroneutralization. Environmental data were analysed using a principal components analysis. The overall IgG seroprevalence rate was 85% (n=367; 95% CI 0.81-0.89). The proximity to sea water, flooded banks and salted mudflats were identified as protective factors. These environmental components are unfavourable to the presence of Culex mosquitoes suggesting that in Senegal, the distribution of the vector species is more limiting for WNV transmission than for the hosts' distribution.
2005 年，在塞内加尔河盆地的五个生态条件迥异的区域对马进行了血清学研究，以评估西尼罗河病毒（WNV）的传播情况，并调查潜在的环境风险因素。在每个研究区域，随机选择马并采集血样。使用两张卫星 ETM+图像构建了五个研究区域的土地覆盖图。使用 ELISA 检测血样中的抗 WNV IgM 和 IgG，并用血清中和试验对阳性样本进行确认。使用主成分分析法分析环境数据。总的 IgG 血清阳性率为 85%（n=367；95%CI 0.81-0.89）。靠近海水、洪水泛滥的河岸和盐泥滩被确定为保护因素。这些环境成分不利于库蚊的存在，这表明在塞内加尔，蚊子传播西尼罗河病毒的分布比宿主分布更受限制。
