Moeser P J, Costello P B, Gillikin S, Murphy T F
Department of Medicine, State University of New York, Buffalo.
Rev Infect Dis. 1991 Jan-Feb;13(1):61-3. doi: 10.1093/clinids/13.1.61.
A 61-year-old man who presented with clinical features suggestive of septic arthritis was found to have acute septic polyarthritis due to Haemophilus influenzae (type b). The clinical and laboratory diagnoses of the case are presented, and the isolates of H. influenzae are characterized. Four isolates recovered from different sites had identical minimal inhibitory drug concentrations, outer membrane protein patterns, and genomic DNA restriction digests. These observations indicate that the disseminated infection arose from a single source. The patient developed antibody to several outer membrane proteins, particularly the P6 protein.
一名61岁男性，临床表现提示为化脓性关节炎，经检查发现是由b型流感嗜血杆菌引起的急性化脓性多关节炎。本文介绍了该病例的临床和实验室诊断情况，并对分离出的流感嗜血杆菌进行了特征分析。从不同部位分离出的4株菌株具有相同的最低抑菌药物浓度、外膜蛋白图谱和基因组DNA限制性酶切图谱。这些观察结果表明，播散性感染源于单一来源。该患者产生了针对几种外膜蛋白的抗体，尤其是P6蛋白。
