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针对儿童严重细菌感染的门诊胃肠外抗生素治疗方案。

A program of outpatient parenteral antibiotic therapy for serious pediatric bacterial infections.

作者信息

Dagan R, Einhorn M

机构信息

Pediatric Infectious Disease Unit, Soroka Medical Center, Beer Sheva, Israel.

出版信息

Rev Infect Dis. 1991 Jan-Feb;13 Suppl 2:S152-5. doi: 10.1093/clinids/13.supplement_2.s152.

DOI:10.1093/clinids/13.supplement_2.s152
PMID:2017643
Abstract

A program set up in the Soroka University Medical Center, Beer Sheva, Israel, offers outpatient parenteral antibiotic therapy (OPAT) for children with serious bacterial infections. The following criteria must be met before a child is placed in this program: OPAT must be a suitable form of treatment for the infection, an appropriate drug must be available, the parents must be cooperative and well-informed, and 24-hour-a-day telephone communication and transportation between the home and hospital must be available. With use of ceftriaxone administered im, the OPAT program has shown positive results: a cure rate of 98.5% and an estimated savings of 1,334 hospital days for 140 patients over a 17-month period.

摘要

以色列贝尔谢巴的索罗卡大学医学中心设立了一个项目,为患有严重细菌感染的儿童提供门诊肠外抗生素治疗(OPAT)。在儿童进入该项目之前,必须满足以下标准:OPAT必须是适合该感染的治疗形式,必须有合适的药物可用,父母必须配合且了解情况,并且家庭与医院之间必须有全天候的电话通讯和交通服务。使用肌内注射头孢曲松的OPAT项目已显示出积极成果:在17个月的时间里,140名患者的治愈率为98.5%,估计节省了1334个住院日。

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引用本文的文献

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Place of parenteral cephalosporins in the ambulatory setting: clinical evidence.胃肠外头孢菌素在门诊环境中的应用:临床证据
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Parenteral cephalosporin therapy in ambulatory care: advantages and disadvantages.门诊护理中的胃肠外头孢菌素治疗:利弊
Drugs. 2000;59 Suppl 3:19-28; discussion 47-9. doi: 10.2165/00003495-200059003-00003.
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Rational prescribing of antibacterials in hospitalised children.住院儿童抗菌药物的合理处方
Pharmacoeconomics. 1996 Dec;10(6):575-93. doi: 10.2165/00019053-199610060-00005.
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Ceftriaxone. A pharmacoeconomic evaluation of its use in the treatment of serious infections.头孢曲松。对其用于治疗严重感染的药物经济学评价。
Pharmacoeconomics. 1994 Sep;6(3):249-69. doi: 10.2165/00019053-199406030-00009.
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Parenteral-oral switch in the management of paediatric pneumonia.小儿肺炎治疗中的肠外-口服转换
Drugs. 1994;47 Suppl 3:43-51. doi: 10.2165/00003495-199400473-00008.