Yaacob I, Harun Z, Ahmad Z
Department of Medicine, Hospital University Sains Malaysia, Kelantan.
Singapore Med J. 1991 Feb;32(1):26-8.
Two hundred and ninety-three bronchoscopies were done for 285 patients (78% males, 22% females) at Hospital University Sains Malaysia between 1984 and 1988. The mean age was 56.4 years (range 13 to 90 years). 70.2% of patients underwent bronchoscopies to confirm or exclude the diagnosis of carcinoma of the bronchus, out of which 58% were confirmed to have bronchial carcinoma. 77% of the 98 patients with visible endobronchial tumours had biopsy specimens diagnostic of malignancy. Brushing and washing cytology increased the positive yield to 92%. The commonest histological type of bronchial carcinoma identified was squamous cell carcinoma (48.1%), followed by small cell carcinoma (27.1%), anaplastic/undifferentiated carcinoma (12.9%), adenocarcinoma (9.4%) and large cell carcinoma (2.4%). Bronchoscopy for the investigation of haemoptysis identified the commonest cause as 'bronchitis'. There were no complications noted in our series. Notable differences of our experience compared to that of the western series were the high percentage of bronchoscopy done for infective respiratory disorders and the younger age of our patients.
1984年至1988年间,马来西亚理科大学医院对285名患者(78%为男性,22%为女性)进行了293次支气管镜检查。平均年龄为56.4岁(范围为13至90岁)。70.2%的患者接受支气管镜检查以确诊或排除支气管癌,其中58%被确诊为支气管癌。98例可见支气管内肿瘤患者中,77%的活检标本诊断为恶性肿瘤。刷检和冲洗细胞学检查使阳性检出率提高到92%。确诊的支气管癌最常见的组织学类型是鳞状细胞癌(48.1%),其次是小细胞癌(27.1%)、间变性/未分化癌(12.9%)、腺癌(9.4%)和大细胞癌(2.4%)。因咯血进行支气管镜检查发现最常见的病因是“支气管炎”。我们的系列研究中未发现并发症。与西方系列研究相比,我们的经验中值得注意的差异在于因感染性呼吸系统疾病进行支气管镜检查的比例较高以及患者年龄较轻。