The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Chem Commun (Camb). 2010 Mar 14;46(10):1637-9. doi: 10.1039/b927031k. Epub 2010 Feb 5.
Deletion of structural elements in cavitand receptors is used to evaluate the thermodynamic and kinetic parameters of binding in these hosts. The use of a bulky guest showcases the importance of host-guest shape adaptations in the molecular recognition process.
空腔受体中环结构元素的缺失被用来评估这些主体中结合的热力学和动力学参数。使用庞大的客体展示了主体-客体形状适应在分子识别过程中的重要性。
