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出生窒息时的电解质状态。

Electrolyte status in birth asphyxia.

机构信息

Department of Biochemistry, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.

出版信息

Indian J Pediatr. 2010 Mar;77(3):259-62. doi: 10.1007/s12098-010-0034-0. Epub 2010 Feb 22.

Abstract

OBJECTIVE

To study electrolyte status in asphyxiated newborns of different severity in early neonatal period and compare with controls.

METHODS

Sodium, potassium and total calcium levels were estimated in the serum samples of asphyxiated newborns of different severity and control group immediately after birth.

RESULTS

Mean serum sodium level was significantly lower (122.1 +/- 6.0 mEq/L vs 138.8 +/- 2.7 mEq/L; P < 0.001), mean serum potassium was higher (5.05 +/- 0.63 mEq/L vs 4.19 +/- 0.40 mEq/L; P < 0.001) and mean serum calcium level was found lower (6.85 +/- 0.95 mg/dl vs 9.50 +/- 0.51 mg/dl; P < 0.001) in cases than controls. Among cases, a strong positive linear correlation was found between the serum sodium, serum calcium levels and their Apgar scores, between sodium levels and total calcium levels and significant negative linear correlation between Apgar scores and serum potassium level.

CONCLUSION

Among cases, hyponatremia and hypocalcemia developed early and simultaneously and the decrease in their serum levels was directly proportional to each other and to the degree of asphyxia. Though, mean potassium level was within the normal limit, the value was higher among cases than controls and directly proportional to asphyxia.

摘要

目的

研究不同严重程度窒息新生儿在新生儿早期的电解质状态,并与对照组进行比较。

方法

在出生后立即测定不同严重程度窒息新生儿和对照组血清样本中的钠、钾和总钙水平。

结果

与对照组相比,窒息新生儿的平均血清钠水平显著降低(122.1 ± 6.0 mEq/L 比 138.8 ± 2.7 mEq/L;P < 0.001),平均血清钾水平升高(5.05 ± 0.63 mEq/L 比 4.19 ± 0.40 mEq/L;P < 0.001),平均血清钙水平降低(6.85 ± 0.95 mg/dl 比 9.50 ± 0.51 mg/dl;P < 0.001)。在病例组中,血清钠、血清钙水平与 Apgar 评分之间呈正相关,钠水平与总钙水平之间呈正相关,Apgar 评分与血清钾水平之间呈负相关。

结论

在病例组中,低钠血症和低钙血症早期同时发生,其血清水平的降低与窒息程度直接相关,且呈正比关系。尽管平均钾水平在正常范围内,但病例组的血清钾水平高于对照组,且与窒息程度呈正比关系。

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