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老年失禁的原因及严重程度评估:一项批判性评价

Evaluation of the causes and severity of geriatric incontinence. A critical appraisal.

作者信息

DuBeau C E, Resnick N M

机构信息

Geriatric Research Education and Clinical Center, Brockton/West Roxbury Department of Veterans Affairs Medical Center, Boston, Massachusetts.

出版信息

Urol Clin North Am. 1991 May;18(2):243-56.

PMID:2017807
Abstract

The evaluation of urinary incontinence in the elderly differs from that in younger patients because of altered or nonspecific disease presentation, the different spectrum of pathophysiology, greater variation between individuals and, in some cases or settings, variable treatment goals. Evaluation must be multifactorial and extend beyond the genitourinary system, because many age-related conditions and the drugs used to treat them can cause or exacerbate urinary incontinence. Voiding records are a reliable measure of severity, although studies of their validity are still lacking. History-taking requires more time in this age group. Stress incontinence symptoms remain very sensitive, whereas obstructive symptoms fall in predictive value. Clinical algorithms based on a combination of symptoms and simple bedside examination and maneuvers may prove most useful in specific settings such as nursing homes. The targeting and interpretation of the physical examination must also change because of age-related conditions (e.g., BPH, atrophic vaginitis) and prevalent comorbid diseases, especially neurologic ones. The Q-tip, elevation, and pessary tests for stress incontinence offer little diagnostic or therapeutic information in the elderly. Routine laboratory tests should be performed to exclude reversible causes of urinary incontinence, while interpretation of the urinalysis must consider the prevalence of asymptomatic bacteriuria. No radiographic studies are routinely needed; bead-chain cystourethrography and IVU in particular probably offer little additional information. Voiding cystourethrography, although little studied, offers dynamic data that may be helpful, especially in evaluating outlet obstruction. Bedside cystometry is simple but may be insensitive to the most prevalent type of detrusor instability in the institutionalized elderly. Finally, multichannel urodynamic study is safe and feasible even in frail elderly patients and should be considered when empiric therapy is risky or has failed, complicated comorbidity exists, or surgery is anticipated.

摘要

由于疾病表现改变或不具特异性、病理生理范围不同、个体差异较大,以及在某些情况或环境下治疗目标各异,老年尿失禁的评估与年轻患者不同。评估必须是多因素的,且要超越泌尿生殖系统,因为许多与年龄相关的病症及其治疗药物可导致或加重尿失禁。排尿记录是严重程度的可靠衡量指标,尽管仍缺乏对其有效性的研究。在这个年龄组中,病史采集需要更多时间。压力性尿失禁症状仍然非常敏感,而梗阻性症状的预测价值则有所下降。基于症状与简单床边检查及操作相结合的临床算法在诸如养老院等特定环境中可能最为有用。由于与年龄相关的病症(如良性前列腺增生、萎缩性阴道炎)和常见的合并症,尤其是神经系统合并症,体格检查的针对性和解读也必须改变。用于压力性尿失禁的棉签试验、抬高试验和子宫托试验在老年人中提供的诊断或治疗信息很少。应进行常规实验室检查以排除尿失禁的可逆性病因,而尿液分析的解读必须考虑无症状菌尿的患病率。通常无需进行影像学检查;尤其是串珠链膀胱尿道造影和静脉肾盂造影可能提供的额外信息很少。排尿性膀胱尿道造影尽管研究较少,但可提供动态数据,可能会有所帮助,特别是在评估出口梗阻时。床边膀胱测压很简单,但可能对机构养老老年人中最常见的逼尿肌不稳定类型不敏感。最后,即使是体弱的老年患者,多通道尿动力学检查也是安全可行的,当经验性治疗有风险或失败、存在复杂的合并症或预期进行手术时,应考虑进行该项检查。

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