Hakkinen P J, Kelling C K, Callender J C
Procter & Gamble Company, Paper Technology Division, Cincinnati, Ohio.
Vet Hum Toxicol. 1991 Feb;33(1):61-5.
A thorough understanding of the routes and magnitudes of chemical exposures that consumers experience during the use of a household product is needed as part of a well-founded risk assessment for that product and its components. This review describes some sources of generic consumer data (eg, relevant body weight or total body surface area for a given human age), and exposure-related data (eg, task frequency and duration) for specific product types needed for exposure assessments. The review also contains a discussion of the importance of statistical characterization of the consumer data (eg, does its range follow a normal, log-normal, or other type of distribution?). The importance of examining these data for correlative interactions is emphasized.
作为对家用产品及其成分进行有充分依据的风险评估的一部分，需要深入了解消费者在使用家用产品过程中所经历的化学暴露途径和暴露量。本综述描述了一些通用消费者数据的来源（例如，给定人类年龄的相关体重或体表面积），以及暴露评估所需的特定产品类型的与暴露相关的数据（例如，任务频率和持续时间）。该综述还讨论了消费者数据统计特征的重要性（例如，其范围是否遵循正态分布、对数正态分布或其他类型的分布？）。强调了检查这些数据以寻找相关相互作用的重要性。
