University of Massachusetts Medical School, Worcester, 01605, USA.
Cell. 2010 Feb 19;140(4):452-4. doi: 10.1016/j.cell.2010.02.005.
The amplification of small RNAs and the assembly of heterochromatin are mutually dependent processes in fission yeast. But which comes first? Halic and Moazed (2010) propose that primal small RNAs initiate the amplification of small interfering RNAs that drive heterochromatin formation and chromatin silencing.
在裂殖酵母中,小 RNA 的扩增和异染色质的组装是相互依赖的过程。但哪个先发生呢?Halic 和 Moazed(2010)提出,原始小 RNA 启动了小干扰 RNA 的扩增,从而驱动异染色质形成和染色质沉默。