靶向效应因子：III 型分泌蛋白的分子识别。
Targeting effectors: the molecular recognition of Type III secreted proteins.
机构信息
Department of Genome Oriented Bioinformatics, Technische Universität München, Wissenschaftszentrum Weihenstephan, 85350 Freising, Germany.
出版信息
Microbes Infect. 2010 May;12(5):346-58. doi: 10.1016/j.micinf.2010.02.003. Epub 2010 Feb 21.
PMID:20178857
Abstract
The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review.
摘要
III 型分泌系统（TTSS）促进了致病性和共生革兰氏阴性细菌效应蛋白向真核宿主细胞质的输出。本文讨论了 TTSS 底物的分子识别的现有功能和进化知识以及分泌信号的计算模型。
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