Lim So-Young, Pyon Jai-Kyong, Mun Goo-Hyun, Bang Sa-Ik, Oh Kap-Sung
Department of Plastic and Reconstructive surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Ann Plast Surg. 2010 Mar;64(3):302-6. doi: 10.1097/SAP.0b013e3181b0bb03.
Tuberculosis is presently an important health problem throughout the world. Despite its progressive decrease in developed countries, the situation has changed in recent years due to the AIDS pandemic. Among these, tuberculous abscess of the chest wall is a rare disease and an optimal treatment plan remains controversial. The authors experienced recalcitrant cases of chest wall cold abscess involving ribs and sternum recurring after local debridement treatment. Nine patients between March 2004 and December 2008 were retrospectively analyzed, focusing on their clinical features, surgical treatment consisting of wide resection and flap coverage, and long-term outcome. There was a past history of pulmonary tuberculosis in 2 patients, but no one had concomitant active pulmonary tuberculosis. Radical resection of soft tissue and the bone resulted in wide defect, which could be covered by a local myocutaneous flap. In all patients, histologic findings of the debrided specimen showed typical lesions of tuberculosis, caseous necrosis with a tuberculoid granulomatous inflammatory infiltrate. Postoperative progress was good and there was no complication of donor site. The patients were started on antituberculosis therapy. They remain well during follow-up period (mean: 22 months). We conclude that cold abscess of the chest wall must be treated more aggressively, and meticulous debridement and wide resection including involved bones and cartilages is required followed by coverage with local muscle or musculocutaneous flaps.
目前,结核病是全球一个重要的健康问题。尽管在发达国家其发病率呈逐渐下降趋势,但近年来由于艾滋病大流行,情况发生了变化。其中,胸壁结核性脓肿是一种罕见疾病,最佳治疗方案仍存在争议。作者遇到了经局部清创治疗后复发的累及肋骨和胸骨的胸壁寒性脓肿的顽固病例。对2004年3月至2008年12月期间的9例患者进行了回顾性分析,重点关注其临床特征、包括广泛切除和皮瓣覆盖的手术治疗以及长期预后。2例患者有肺结核病史,但均无合并活动性肺结核。软组织和骨骼的根治性切除导致广泛缺损,可通过局部肌皮瓣覆盖。所有患者清创标本的组织学检查结果均显示典型的结核病变,即干酪样坏死伴结核样肉芽肿性炎症浸润。术后恢复良好,供区无并发症。患者开始接受抗结核治疗。在随访期间(平均22个月)他们情况良好。我们得出结论,胸壁寒性脓肿必须更积极地治疗,需要进行细致的清创和广泛切除,包括受累的骨骼和软骨,随后用局部肌肉或肌皮瓣覆盖。