Ural State Technical University, 19 Mira St, Ekaterinburg, Russia.
Bull Math Biol. 2010 Oct;72(7):1912-24. doi: 10.1007/s11538-010-9520-9. Epub 2010 Feb 24.
A model of the active transport of ions in the Cascinodiscus wailesii diatom cell is constructed taking into account the transport of H(+), Na(+), K(+), Ca(+2), NO(3)(-), Cl(-), and NH(4)(+) ions. This model allows calculating intracellular concentrations of basic ions and the biomembrane resting potential. A hierarchical algorithm "one ion--one transport system" is used in the model. The dependence of the resting potential on the extracellular concentration of potassium is plotted in terms of the model. The calculated values are in good agreement with the corresponding experimental data.
构建了一个考虑到 Cascinodiscus wailesii 硅藻细胞中 H(+)、Na(+)、K(+)、Ca(+2)、NO(3)(-)、Cl(-)和 NH(4)(+)离子主动运输的模型。该模型允许计算基本离子的细胞内浓度和生物膜静息电位。模型中使用了“一个离子-一个运输系统”的分层算法。根据模型绘制了静息电位与细胞外钾浓度的关系。计算值与相应的实验数据吻合良好。
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