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期待治疗剖宫产瘢痕妊娠:两例病例报告及自然病程初探。

Expectant treatment of cesarean scar pregnancy: two case reports and a glimpse at the natural courses.

机构信息

Department of Obstetrics and Gynecology, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.

出版信息

Arch Gynecol Obstet. 2010 Oct;282(4):455-8. doi: 10.1007/s00404-010-1391-7. Epub 2010 Feb 24.

Abstract

OBJECTIVE

Pregnancy in previous cesarean scar is the rarest form of ectopic pregnancy. Little is known about its natural history and optimal management. All except one reported case in the literature that were treated expectantly either become unsuccessful or complicated. We aimed to present two cases of cesarean scar pregnancy (CSP) that were managed expectantly to discuss the value of this management and have a glimpse of the natural courses of certain CSPs.

CASES

We present two cases of parous women with complaint of amenorrhea and mild bleeding. Sonography and magnetic resonance imaging (MRI) revealed the diagnosis of CSP without viable gestational sac. The patients opted for expectant treatment. We closely monitored the patients with a detailed plan.

RESULTS

In case 1, the patient had mild bleeding during monitoring and her serum betaHCG dropped quickly to normal range after 7 weeks. She was fully recovered with total absorption of the mixed mass in the scar of the anterior wall of the uterus. In case 2, the patient had laparoscopy after expectant management for 16 weeks because her serum betaHCG reached a plateau between 30 and 40 mIU/mL for 4 weeks and there was no obvious resorption of the mixed mass within the lower anterior wall of the uterus. The histopathology revealed decidualized villa within organizing tissue and the patient recovered uneventfully.

CONCLUSIONS

CSP with no viable gestation sac and rapidly decreased serum betaHCG level can be expectantly treated. The natural history of such CSPs may be naturally demised.

摘要

目的

剖宫产瘢痕妊娠是最罕见的异位妊娠形式。人们对其自然史和最佳治疗方法知之甚少。除了文献中报道的一例经期待治疗的病例外,其余病例均不成功或变得复杂。我们旨在报告两例经期待治疗的剖宫产瘢痕妊娠(CSP)病例,以讨论这种治疗方法的价值,并对某些 CSP 的自然病程有一定的了解。

病例

我们报告了两例有停经和轻微出血主诉的经产妇。超声和磁共振成像(MRI)显示 CSP 无活胎囊的诊断。患者选择期待治疗。我们密切监测患者,并制定了详细的计划。

结果

在病例 1 中,患者在监测期间出现轻微出血,其血清β-HCG 在 7 周后迅速降至正常范围。她完全恢复,子宫前壁瘢痕内的混合包块完全吸收。在病例 2 中,患者在期待治疗 16 周后行腹腔镜检查,因为她的血清β-HCG 在 30 至 40 mIU/mL 之间稳定了 4 周,且子宫前下壁的混合包块无明显吸收。组织病理学显示为有组织化的蜕膜化绒毛,患者恢复顺利。

结论

无活胎囊且血清β-HCG 水平迅速下降的 CSP 可以期待治疗。这种 CSP 的自然病程可能会自然消退。

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