Columbia University Medical Center, Department of Psychiatry, USA.
Am J Drug Alcohol Abuse. 2009;35(5):368-74. doi: 10.1080/00952990903108256.
The purpose of the present study was to assess the association between substance use/diagnosis and sexual risk behaviors among women enrolled in both psychosocial outpatient (PS) and methadone maintenance (MM) treatment and involved in a HIV prevention intervention study within the National Institute for Drug Abuse Clinical Trials Network.
515 sexually active women reported on unprotected sexual occasions (USO), anal sex, sex trading, sex with drug occasions, and multiple male sex partners at the baseline assessment.
Within the PS sample, cocaine use diagnosis was associated with more than twice the risk of having multiple partners, trading sex for drugs, having anal sex, or having sex with drugs; alcohol or opioid use diagnosis was associated with fewer risk behaviors. Within the MM sample, cocaine use, alcohol use and opiate use diagnoses were each associated with one to two risk behaviors. Associations between sexual risk and substance using days were less frequent in both samples.
These findings highlight the need for integration of HIV sexual prevention interventions that address the relationship between sexual risk behavior and substance use diagnoses into substance abuse treatment programs.
本研究旨在评估参加心理社会门诊(PS)和美沙酮维持(MM)治疗并参与国家药物滥用研究所临床试验网络内艾滋病毒预防干预研究的女性中物质使用/诊断与性风险行为之间的关联。
515 名有性行为的女性在基线评估时报告了无保护性行为(USO)、肛交、性交易、与毒品发生性关系和多个男性性伴侣的情况。
在 PS 样本中,可卡因使用诊断与具有多个伴侣、性交易、肛交或与毒品发生性关系的风险增加两倍以上有关;酒精或阿片类药物使用诊断与较少的风险行为有关。在 MM 样本中,可卡因使用、酒精使用和阿片类药物使用诊断各与一种至两种风险行为相关。在这两个样本中,性风险与物质使用天数之间的关联较少。
这些发现强调需要将针对性风险行为与物质使用诊断之间关系的艾滋病毒性预防干预措施纳入物质滥用治疗计划。