Department of Psychiatry, Columbia University Medical Center, New York, New York, USA. lc21302columbia.edu
Am J Drug Alcohol Abuse. 2009;35(5):305-10. doi: 10.1080/00952990903060127.
Substance use and a history of childhood sexual abuse (CSA) are risk factors for unprotected sex among women, yet questions remain as to how their combined influence may differentially affect sexual risk.
The current study investigated how complex relationships among drug use and CSA may contribute to unprotected sexual occasions (USO).
A Generalized Linear Mixed Model was used to examine the interaction between current cocaine/stimulants and opioid use and CSA on number of USOs in a sample of 214 sexually active women in outpatient methadone maintenance treatment.
For women with CSA, an increase in days of cocaine/stimulant use was associated with a significant increase in USOs. In contrast, an increase in days of opiate use was associated with a significant decrease in USOs. For the group of women who did not report CSA, there was a significant increase in USOs with increased opiate use.
Findings indicate that CSA is related to unprotected sexual occasions depending on drug type and severity of use.
Women with CSA using cocaine are at particularly high risk for having unprotected sex and should be specifically targeted for HIV prevention interventions.
药物使用和儿童期性虐待(CSA)史是女性无保护性行为的风险因素,但它们的综合影响如何对性风险产生差异影响仍存在疑问。
本研究调查了药物使用和 CSA 之间复杂的关系如何导致无保护性行为(USO)。
在一项 214 名接受门诊美沙酮维持治疗的活跃女性样本中,使用广义线性混合模型检验了当前可卡因/兴奋剂和阿片类药物使用与 CSA 对 USO 次数的交互作用。
对于有 CSA 的女性,可卡因/兴奋剂使用天数的增加与 USO 的显著增加有关。相比之下,阿片类药物使用天数的增加与 USO 的显著减少有关。对于没有报告 CSA 的女性群体,阿片类药物使用的增加与 USO 的显著增加有关。
研究结果表明,CSA 与性保护行为的发生有关,具体取决于药物类型和使用严重程度。
使用可卡因的 CSA 女性发生无保护性行为的风险特别高,应特别针对她们进行 HIV 预防干预。