Teixeira Rodrigo P, Reid Julie A, Greensmith Andrew
Cleft Palate Craniofac J. 2011 Jul;48(4):473-7. doi: 10.1597/09-024. Epub 2010 Feb 22.
Soft tissue augmentation of the posterior pharyngeal wall and the soft palate is reported to reduce velopharyngeal incompetence, and fat grafting in selected patients has shown effective and lasting results for restoring normal resonance. Potential complications of soft tissue augmentation for velopharyngeal incompetence include obstructive sleep apnea.
An 8-year-old boy with velopharyngeal incompetence and a small velopharyngeal gap underwent a fat injection procedure and subsequently developed obstructive sleep apnea concomitant with a significant weight gain. Videofluoroscopy and nasendoscopy showed a remarkable enlargement of the grafted fat areas that required a soft palate debulking procedure, significantly improving obstructive sleep apnea.
This is an unusual case where alteration in volume of grafted fat at the recipient site is suspected of causing obstructive sleep apnea. It is also an example of long-term fat graft survival and fat graft overgrowth.
据报道，咽后壁和软腭的软组织增厚可减少腭咽闭合不全，对部分患者进行脂肪移植已显示出恢复正常共鸣的有效且持久的效果。腭咽闭合不全的软组织增厚的潜在并发症包括阻塞性睡眠呼吸暂停。
一名8岁男孩患有腭咽闭合不全且腭咽间隙较小，接受了脂肪注射手术，随后随着体重显著增加出现了阻塞性睡眠呼吸暂停。电视荧光透视检查和鼻内镜检查显示移植脂肪区域明显增大，需要进行软腭减容手术，这显著改善了阻塞性睡眠呼吸暂停。
这是一例罕见病例，怀疑受区移植脂肪体积改变导致阻塞性睡眠呼吸暂停。这也是长期脂肪移植存活和脂肪移植过度生长的一个例子。
