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聚乙二醇化干扰素-α2a和利巴韦林治疗慢性丙型肝炎感染相关的间质性肺炎:一例报告

Interstitial pneumonitis associated with pegylated interferon-alpha 2a and ribavirin for chronic hepatitis C infection: a case report.

作者信息

Atug Ozlen, Akin Hakan, Alahdab Yesim Ozen, Ceyhan Berrin, Tozun Nurdan, Ozdogan Osman

机构信息

Department of Gastroenterology, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Cases J. 2009 Mar 10;2:6464. doi: 10.1186/1757-1626-0002-0000006464.

Abstract

Interstitial pneumonitis is a rare but potentially fatal side effect occurring from 2 weeks to 16 weeks after the initiation of treatment with pegylated interferon alpha and ribavirin for chronic hepatitis C.Herein, we present a 68-year-old man with chronic hepatitis C virus infection who developed interstitial pneumonitis association with pegylated interferon after 36 weeks initiation of pegylated interferon-alpha and ribavirin therapy. He did not recover after discontinuation of pegylated interferon/ribavirin and improved by steroid therapy.

摘要

间质性肺炎是聚乙二醇化干扰素α和利巴韦林治疗慢性丙型肝炎开始后2周~16周出现的一种罕见但可能致命的副作用。在此,我们报告一名68岁慢性丙型肝炎病毒感染男性患者,在聚乙二醇化干扰素α和利巴韦林治疗开始36周后发生了与聚乙二醇化干扰素相关的间质性肺炎。停用聚乙二醇化干扰素/利巴韦林后他未恢复,经类固醇治疗后病情改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a0c/2827138/9dc34c1a57e6/1757-1626-0002-0000006464-1.jpg

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