Kuiper Michael A, Peikert Nicole, Boerma E Christiaan
Department of Intensive Care Medicine, Medical Centre Leeuwarden, P.O. Box 888, 8901 BR Leeuwarden, The Netherlands; Department of Intensive Care Medicine, Academic Medical Centre Amsterdam Hermes Critical Care Group, The Netherlands.
Cases J. 2009 Mar 25;2:6530. doi: 10.1186/1757-1626-2-6530.
To raise awareness among health care workers of the risk of withdrawal symptoms after longstanding and intense abuse of gamma-hydroxybutyric acid.
A 23 year old Caucasian woman presented with gamma-hydroxybutyric addiction and withdrawal syndrome. The symptoms of gamma-hydroxybutyric withdrawal in this patient initially went unrecognized, upon which her situation deteriorated in such a way that she needed to be admitted to the Intensive Care Unit for airway protection and mechanical ventilation. Treatment with high doses of benzodiazepines led to liberation of the ventilator and further recovery.
Withdrawal symptoms of gamma-hydroxybutyric addiction are often not well recognized and the responsible physicians at Emergency Department, Intensive Care Unit and the Psychiatry ward need better understanding of diagnose and treatment. Gamma-hydroxybutyric acid withdrawal is potentially life threatening and its management may require a multidisciplinary approach. Early recognition of gamma-hydroxybutyric acid withdrawal may lead to better management of these patients.
提高医护人员对长期大量滥用γ-羟基丁酸后出现戒断症状风险的认识。
一名23岁的白种女性出现γ-羟基丁酸成瘾及戒断综合征。该患者γ-羟基丁酸戒断症状最初未被识别，随后病情恶化，以至于需要入住重症监护病房以保护气道并进行机械通气。大剂量苯二氮䓬类药物治疗使患者脱机并进一步康复。
γ-羟基丁酸成瘾的戒断症状常未得到充分认识，急诊科、重症监护病房及精神科的责任医生需要更好地了解其诊断和治疗方法。γ-羟基丁酸戒断可能危及生命，其处理可能需要多学科方法。早期识别γ-羟基丁酸戒断可能有助于更好地管理这些患者。
