Burke Neil G, McCaffrey D, Mackle E
Department of General Surgery, Craigavon Area Hospital, 68 Lurgan Road, Portadown, Northern Ireland, BT63 5QQ, UK.
Cases J. 2009 Sep 9;2:7619. doi: 10.1186/1757-1626-0002-0000007619.
Tissue contamination is a common occurrence in pathology, but surgeons are relatively unaware of this. We present the case of a 45-year-old man with Barrett's oesophagus, in which the histology of routine biopsies of an asymptomatic patient, were reported as 'carcinoma in situ'. Further biopsies were taken over a three month period but showed no evidence of malignancy. Tissue contamination or 'cross over' was identified as the likely cause of the abnormal result. This case report highlights the importance of the correlation of the clinical and histopathological findings and tissue contamination should be considered when both of these findings are not consistent.
组织污染在病理学中很常见,但外科医生对此相对缺乏认识。我们报告一例45岁患有巴雷特食管的男性病例,该无症状患者常规活检的组织学报告为“原位癌”。在三个月的时间里又进行了进一步的活检,但未发现恶性肿瘤的迹象。组织污染或“交叉污染”被确定为异常结果的可能原因。本病例报告强调了临床和组织病理学检查结果相互关联的重要性,当这两项检查结果不一致时,应考虑组织污染的可能性。