Institute of Inorganic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
J Colloid Interface Sci. 2010 May 15;345(2):200-5. doi: 10.1016/j.jcis.2010.01.070. Epub 2010 Feb 1.
The cocondensation of 3-iodopropyltrimethoxysilane and tetraethoxysilane with an additional substituted trimethoxysilane (RTMS) in the presence of Pluronic P123 and hydrogen iodide yields bifunctionalized mesoporous silica. The pore-size distribution of these materials depends on the nature of the RTMS additive. Excellent results in terms of a narrow pore-size distribution were obtained with methyltrimethoxysilane. A particularly interesting bifunctionalized mesoporous material is formed by the coinclusion of iodopropyl and aminopropyl moieties. The complementary reactivity of these two functional groups is demonstrated by the selective labeling of the amino-iodo-functionalized mesoporous silica with 2-hydroxy-substituted Nile red and fluorescein isothiocyanate, allowing further characterization of the functional group distribution by confocal laser scanning microscopy.
3-碘丙基三甲氧基硅烷和四乙氧基硅烷与另外一种取代的三甲氧基硅烷（RTMS）在 Pluronic P123 和碘化氢存在下缩合，得到双官能化的介孔硅。这些材料的孔径分布取决于 RTMS 添加剂的性质。用甲基三甲氧基硅烷可以得到非常好的窄孔径分布的结果。通过包含碘丙基和氨丙基部分，可以形成特别有趣的双官能化介孔材料。这两个官能团的互补反应性通过用 2-羟基取代的尼罗红和异硫氰酸荧光素选择性标记氨基碘功能化的介孔硅来证明，从而通过共聚焦激光扫描显微镜进一步表征官能团的分布。
