Department of Neurology, Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
Epilepsy Behav. 2010 Apr;17(4):561-4. doi: 10.1016/j.yebeh.2010.01.022. Epub 2010 Feb 23.
We describe a patient with seizures arising from right anterior-inferior frontal lobe presenting as myoclonic epilepsy. A 19-year-old man had experienced frequent paroxysmal bilateral myoclonic jerks involving his upper arms, shoulders, neck, and upper trunk since the age of 10. His baseline EEG showed intermittent right frontal spikes, and his ictal EEG showed rhythmic sharp theta discharges in the same area. MRI revealed cortical dysplasia in the right inferior frontal gyrus, and ictal-interictal SPECT analysis by SPM showed increased signal abnormality in this region. Diffusion tensor imaging (DTI) showed defects in fasciculi in the same area. These findings suggest that frontal lobe epilepsy should be considered in some patients with myoclonic seizures.
我们描述了一例起源于右侧额下回前部的癫痫发作患者，表现为肌阵挛性癫痫。一名 19 岁男性自 10 岁起经常出现阵发性双侧上肢、肩部、颈部和上胸部的肌阵挛性抽搐。他的基础脑电图显示间歇性右侧额部棘波，发作期脑电图显示同一区域的节律性尖锐θ放电。MRI 显示右侧额下回皮质发育不良，SPM 分析的发作期-发作间期 SPECT 显示该区域信号异常增加。弥散张量成像（DTI）显示同一区域束纤维缺陷。这些发现提示，对于一些出现肌阵挛性发作的患者，应考虑额叶癫痫。
