Departamento de Microbiologia, Universidade Federal de São Paulo, São Paulo, Brazil.
J Clin Microbiol. 2010 Apr;48(4):1452-5. doi: 10.1128/JCM.01944-09. Epub 2010 Feb 24.
The presence of the pathogenicity island (PAI) O122 genes, efa1 (lifA), sen, pagC, nleB, and nleE, in typical and atypical enteropathogenic Escherichia coli (EPEC) strains was investigated. The simultaneous occurrence of all genes was statistically associated with diarrhea due to atypical EPEC. Detection of the complete PAI O122 could aid in the identification of potential pathogenic strains of atypical EPEC.
本研究调查了致病性岛(PAI)O122 基因efa1(lifA)、sen、pagC、nleB 和 nleE 在典型和非典型肠致病性大肠杆菌(EPEC)菌株中的存在情况。所有基因的同时存在与非典型 EPEC 引起的腹泻具有统计学关联。检测完整的 PAI O122 有助于鉴定非典型 EPEC 的潜在致病菌株。